The Hidden Dangers of Retinoids No One Talks About
Retinoids have become one of the most talked-about ingredients in skincare. Known for their ability to promote smoother, clearer, and younger-looking skin, these vitamin A derivatives are now common in many skincare routines. However, doctors caution that while the results can be impressive, retinoids side effects should never be ignored.
Recently, Dr. Sermed Mezher, a family medicine physician and medical content creator, explained in a video why understanding both the benefits and risks of retinoids is essential before using them.
What Are Retinoids and How Do They Work?
Retinoids work by speeding up the skin’s natural renewal process and stimulating collagen production, which helps improve skin tone, smooth fine lines, and unclog pores. This makes them highly effective for treating acne, uneven texture, and early signs of ageing.
However, any product that produces a biological effect in the body can also lead to side effects. The same mechanisms that make retinoids effective can also make the skin more sensitive and reactive.
Why Do Retinoids Cause Flaking and Peeling?
In his explanation, Dr. Mezher referred to a common reaction many first-time users experience: peeling, flaking, or irritation. This happens because retinoids accelerate skin turnover, causing old, dead skin cells to shed more quickly. As new, delicate skin emerges, it may feel dry, tight, or even slightly inflamed.
He added that this phase is often temporary, but users must approach the process gradually and with proper skin care to avoid unnecessary irritation.
Common Retinoids Side Effects You Should Know
While retinoids can truly “give you a whole new skin,” certain side effects are common, especially in the early weeks of use. These include:
- Increased Sun Sensitivity: The faster cell renewal process can expose newer skin layers, making them more prone to sunburn and UV damage.
- Redness or Burning Sensation: Retinoids can interact with the TRPV1 receptor, the same receptor activated by chilli’s heat compound (capsaicin), leading to redness, stinging, or mild burning.
- Dryness and Flakiness: Reduced oil production in the skin’s glands can lead to dryness and a tight feeling.
- Unsuitable During Pregnancy: Retinoids are not recommended for pregnant individuals due to potential risks to fetal development.
How to Minimize Retinoid Side Effects
- Apply Sunscreen (SPF 50): Protect your skin from harmful UV rays daily, even indoors.
- Use a Gentle, Non-Comedogenic Moisturizer: Hydrating the skin helps reduce dryness and irritation.
- Practice Sun Avoidance: Limit direct sun exposure and use hats or protective clothing when outdoors.
- Start Slowly: Begin with lower concentrations and apply retinoids only a few times a week before increasing frequency.
Doctor’s Final Advice
Dr. Mezher reminded users that every active treatment interacts with the body’s natural pathways, and these interactions are rarely isolated. That means even beneficial ingredients can cause mild or temporary side effects.
“The key,” he said, “is to weigh the benefits against the risks and to use these products under medical guidance. With proper precautions, the positive effects of retinoids far outweigh the manageable side effects.”
Conclusion
Retinoids can truly rejuvenate your skin, improving texture, brightness, and signs of ageing, but awareness of retinoids’ side effects is crucial for safe and effective results. Always start slow, stay consistent with sun protection, and when in doubt, seek professional advice before beginning any new skincare treatment.
Source:Â Inputs from various media SourcesÂ
I’m a pharmacist with a strong background in health sciences. I hold a BSc from Delhi University and a pharmacy degree from PDM University. I write articles and daily health news while interviewing doctors to bring you the latest insights. In my free time, you’ll find me at the gym or lost in a sci-fi novel.
- Priya Bairagi
- Health News and Updates,People Forum
- 27 October 2025
- 09:00








