Sinapic acid found to speed up wound healing
A team of researchers from Nagaland University has made a groundbreaking discovery that could change how diabetic wounds are treated. The team identified Sinapic acid, a natural plant compound, as a safe and effective substance that can significantly speed up wound healing in diabetic patients.
This remarkable finding opens doors for natural, affordable, and side-effect-free treatments for one of the most serious complications of diabetes, chronic, slow-healing wounds.
A Natural Solution to a Global Health Challenge
Diabetes affects hundreds of millions worldwide, and one of its most distressing complications is delayed wound healing. Many patients develop diabetic foot ulcers, which often lead to severe infections or even amputations. Current treatments use synthetic drugs that can be expensive, less effective and sometimes cause unwanted side effects.
To address this, researchers explored Sinapic acid, a naturally occurring antioxidant in many edible plants. Their findings show that when administered orally, Sinapic acid can activate the body’s healing pathways and restore tissue repair mechanisms in diabetic wounds.
How Sinapic Acid Speeds Up Healing
According to the research, Sinapic acid works by activating the SIRT1 pathway, a key biological route that helps control tissue regeneration, new blood vessel formation (angiogenesis), and inflammation. This means the compound not only helps wounds close faster but also improves the quality of healing and reduces infection risks.
Interestingly, the study also revealed that a lower dose (20 mg/kg) was more effective than a higher one (40 mg/kg), a phenomenon known as the “Inverted Dose-Response.” This insight could help scientists design safer and more efficient therapies in the future.
University Leaders Hail the Discovery
Prof. Jagadish K. Patnaik, Vice Chancellor of Nagaland University, praised the research team, saying this discovery underscores the university’s commitment to tackling pressing health challenges through innovation and scientific excellence.
He emphasized that the identification of Sinapic acid as a potential natural treatment for diabetic wounds demonstrates the power of research rooted in nature to improve global healthcare outcomes.
From Laboratory to Real-World Application
The researchers are now focusing on translating this success into practical therapeutic use. Future studies will include:
- Detailed molecular investigations of pathways like PI3K/Akt and NF-ÎşB
- Toxicity and pharmacokinetic profiling to confirm safety
- Formulation development for capsules or nutraceutical tablets
- Pilot clinical trials in diabetic patients to test real-world efficacy and safety
If successful, Sinapic acid could become an affordable, natural oral therapy for diabetic wound management, especially beneficial for patients in rural or resource-limited settings where access to advanced healthcare is restricted.
Conclusion
The discovery of Sinapic acid as a potential treatment marks a major advancement in diabetic wound care. By harnessing nature’s own compounds, scientists may soon offer patients a safer, more accessible way to heal, reducing the risk of amputations and improving recovery times.
This research not only represents a scientific milestone for Nagaland University but also shines as an inspiring example of how natural compounds can pave the way for the next generation of medical breakthroughs.
Source:Â Inputs from various media SourcesÂ
I’m a pharmacist with a strong background in health sciences. I hold a BSc from Delhi University and a pharmacy degree from PDM University. I write articles and daily health news while interviewing doctors to bring you the latest insights. In my free time, you’ll find me at the gym or lost in a sci-fi novel.
- Health News and Updates,People Forum
- 22 October 2025
- 20:00
