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The Aartery Chronicles - Malaria Vaccine

WHO’s Call for Widespread Use of the Malaria Vaccine

Reading Time: 4 minutesWHO’s Call for Widespread Use of the Malaria Vaccine Malaria is a serious disease that is caused due to parasites of the genus Plasmodium. The parasites get transmitted by the bite of a female-infected mosquito. The disease is primarily seen in tropical and sub-tropical areas where the climate is favourable for the breeding of vectors that transmit parasites. Malaria is treatable and preventable. Out of five Plasmodium parasites, P. falciparum is believed to be the deadliest and it is mostly prevalent in African countries. The unicellular protozoan parasites of malaria that belong to the genus Plasmodium have five types: falciparum malariae vivax ovale knowles  P.vivax and P. ovale may cause less severe forms of malaria, but they can still pose dangers. P. malariae and P. knowlesi are also malaria parasites, with P. knowlesi primarily infecting macaques but occasionally affecting humans, potentially causing severe disease. Incubation Period: After an infective bite of an Anopheles mosquito, the incubation period usually varies depending on the species of Plasmodium.  Typically, malaria symptoms appear within an incubation period of about 7 to 30 days. Most of the time shorter incubation periods are noticed with P. falciparum while longer incubation periods are more common with P. malariae. This variation in the incubation period is one of the factors that make diagnosing and treating malaria challenging. Symptoms of Malaria: People suffering from malaria may experience cycles of malarial ‘attacks’. These attacks begin with chills and shivering, leading to high fever and sweating. Severe symptoms are more likely to occur in newborns, children under 5 years, pregnant women, travellers, and those with HIV or AIDS. Some of the common symptoms of malaria: Fatigue Fever & chills Headache Cough Rapid breathing Abdominal pain Diarrhea Muscle and joint pain Sweats Anti malaria campaign in Qatiff [wikimedia commons] WHO Endorses Widespread Use of RTS, S/AS01 Malaria Vaccine in Malaria-Prone Regions The World Health Organization (WHO) advocates the extensive adoption of the RTS, S/AS01 (RTS, S) malaria vaccine for the prevention of malaria in children. The vaccination is advised for children living in areas with high transmission rates of P. falciparum malaria. RTS, S/AS01 is known to be the most successful vaccine so far. It was discovered that the vaccine can prevent disease in young children by up to 80%. WHO recommends the provision of vaccines to children from 5 months of age in a schedule of 4 doses to reduce the burden and malaria disease. Malaria is a prominent cause of death and childhood illness in African countries. Around 260,000 children in Africa under the age of five lose their lives to malaria annually. Reportedly, WHO has been accounting for the stagnation in the progression of malaria. The WHO Director Dr Tedros Adhanom Ghebreyesus has signified this as a historic moment and said that “The long-awaited vaccine for malaria is a scientific breakthrough for child health and control of malaria” The data and generated insights from the two years of vaccination have revealed key findings of the vaccine: Feasible delivery: With good and equitable coverage of RTS, S shown through routine vaccination systems, the introduction of vaccines is feasible. Safety: The vaccine was found to have a favourable safety profile and has reached more than two-thirds of children in three countries. Cost-effectivity and high impact: In areas with moderate to high malaria transmission, the vaccine is estimated to be cost-effective and there has been a significant reduction in deadly severe malaria. The R21/Matrix-M™ malaria vaccine, a collaborative creation of the University of Oxford and the Serum Institute of India, utilizing Novavax’s adjuvant technology, has received the World Health Organization’s (WHO) endorsement following adherence to the necessary safety, quality, and efficacy criteria. Author: Ms Sanika Pande Health Updates Medicine An Analysis of Abortion Laws in the United States Celebrating National Doctor's Day: Prioritizing Regular Health Checkups for a Happier & Healthier Life National Doctor's Day Trauma on the Tracks: High Time to Address PTSD in India Mitigating Health Risks in the Aftermath of Floods: A Clinical Perspective Monsoon Woes: Rise in Eye Flu cases all over India

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Top 10 Environmental Hazards & Policies Protecting Ecosystems

Reading Time: 12 minutesTop 10 Environmental Hazards & Policies Protecting Health & Ecosystems Environmental hazards pose a significant and ever-growing threat to public health and ecosystems worldwide. Medical professionals play a pivotal role in understanding, addressing, and mitigating the health effects of these hazards. In this comprehensive article, we delve into the top 10 environmental hazards, their clinical implications, and the global policies and initiatives that are actively working to combat these threats, contributing to a healthier and more sustainable world. Air Pollution: Air pollution represents a pressing and pervasive environmental challenge that has far-reaching consequences for both the natural world and human health. This complex issue is primarily propelled by various anthropogenic activities, with the prominent culprits being industrial emissions, vehicular exhaust, and the widespread combustion of fossil fuels. These sources release a plethora of harmful pollutants into the atmosphere, including particulate matter, nitrogen oxides, sulfur dioxide, volatile organic compounds, and carbon monoxide, among others.   The clinical implications of air pollution are profound and multi-faceted. Prolonged exposure to polluted air has been linked to a wide array of health problems, with respiratory diseases being among the most prominent. Conditions such as asthma, chronic obstructive pulmonary disease (COPD), and bronchitis are exacerbated by the inhalation of airborne pollutants. Moreover, air pollution is a significant contributor to cardiovascular diseases, as it can lead to inflammation, oxidative stress, and the narrowing of blood vessels, ultimately increasing the risk of heart attacks and strokes.   Furthermore, individuals with pre-existing health conditions are particularly vulnerable, as air pollution can exacerbate their ailments. It also poses a serious threat to children, whose developing respiratory systems are more susceptible to damage. In summary, the insidious nature of air pollution makes it imperative for societies to take concerted action to mitigate its harmful effects, both for the sake of public health and the preservation of the environment.   Global Policy Response: The World Health Organization (WHO) has been at the forefront of addressing air pollution. The “BreatheLife” campaign, in partnership with the United Nations Environment Programme (UNEP) and the Climate and Clean Air Coalition, seeks to reduce air pollution and its impact on public health through policy advocacy, awareness campaigns, and the promotion of clean energy solutions. Water Contamination Contaminated water sources present a grave and far-reaching threat to public health, giving rise to a myriad of ailments and long-term health concerns. The contamination of water supplies can occur through various means, including the presence of microbial pathogens, chemicals, and heavy metals. These contaminants can lead to a host of waterborne diseases, with cholera being a notorious example. Waterborne diseases are often characterized by severe gastrointestinal symptoms, such as diarrhoea and vomiting, which can lead to dehydration and, in extreme cases, even death.   Moreover, contaminated water sources can cause a wide range of gastrointestinal infections, impacting individuals of all ages. These infections can result from exposure to pathogens like E. coli and Giardia, which thrive in unsanitary water conditions. The consequences can be particularly dire in communities lacking access to clean drinking water and proper sanitation facilities.   Beyond immediate health risks, long-term exposure to water contaminants, including heavy metals like lead, arsenic, and mercury, can have profound and lasting effects on human health. These substances can accumulate in the body over time, leading to chronic health conditions such as neurological disorders, developmental delays in children, and various forms of cancer.   To safeguard public health, it is imperative that efforts be made to ensure access to clean and safe drinking water sources, along with robust water treatment and monitoring systems. Addressing water contamination is not only a matter of immediate well-being but also a crucial aspect of preventing long-term health problems for communities around the world.   Global Policy Response: The United Nations Sustainable Development Goal 6 (SDG 6) aims to ensure access to clean water and sanitation for all by 2030. This global commitment underscores the importance of clean water sources and sanitation systems in safeguarding public health. Climate Change Climate change is a multifaceted and all-encompassing environmental challenge, wielding a profound influence on public health. This complex issue is characterized by a range of detrimental clinical impacts that extend across various domains. One of the most visible consequences of climate change is the surge in heat-related illnesses. As global temperatures rise, heatwaves become more frequent and severe, increasing the risk of conditions such as heat exhaustion and heatstroke. Vulnerable populations, including the elderly and individuals with pre-existing health conditions, are especially susceptible.   Another worrisome clinical implication of climate change is the proliferation of vector-borne diseases. Rising temperatures and altered precipitation patterns create favourable conditions for disease-carrying vectors like mosquitoes and ticks. This has led to the expansion of diseases such as malaria, dengue fever, and Lyme disease into previously unaffected regions, posing significant health threats.   Additionally, climate-induced stress and anxiety have emerged as critical mental health issues. The far-reaching impacts of climate change, including extreme weather events, displacement due to rising sea levels, and food insecurity, can contribute to a sense of insecurity and despair. This can lead to various mental health concerns, including depression, anxiety, and post-traumatic stress disorder.   Addressing climate change is thus not only an environmental imperative but also a crucial element of safeguarding public health. Mitigation efforts to reduce greenhouse gas emissions and adaptation strategies to protect vulnerable populations are essential steps toward minimizing the clinical consequences of climate change and ensuring a healthier and more resilient future for all.   Global Policy Response: The Paris Agreement, adopted in 2015, is a landmark international treaty aimed at mitigating climate change. Its central goal is to limit global warming to well below 2 degrees Celsius above pre-industrial levels. Countries that are signatories to the agreement have pledged to reduce greenhouse gas emissions and transition to a low-carbon economy. Chemical Exposure Exposure to industrial chemicals and pesticides presents a significant and wide-ranging threat to human health, leading to a variety of serious clinical issues. These hazardous substances, often encountered

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