This New Sensor Detects Cholesterol in Seconds

Researchers from the Institute of Advanced Study in Science and Technology (IASST), Guwahati, have developed an innovative and sustainable solution to detect cholesterol early. Backed by the Department of Science and Technology (DST), the team has created an optical sensor using silk fibre and phosphorene quantum dots—a combination that is both effective and environmentally friendly.

How the Sensor Works

This newly developed device is capable of identifying cholesterol even in very small amounts—below the normal range. This early detection is essential for timely diagnosis and treatment of various health conditions. The researchers integrated the silk material into a cellulose nitrate membrane to build an electrical sensing platform. As a result, the device does not generate any electronic waste, making it a greener alternative to conventional methods.

Why Early Detection Matters

Cholesterol is a fat-like substance produced by the liver and is essential for the body. It helps in the formation of  Vitamin D, bile acids, and hormones. However, abnormal cholesterol levels—especially high LDL (low-density lipoprotein) or “bad” cholesterol—can lead to serious conditions such as:

• Atherosclerosis
• Heart attacks (myocardial infarction)
• Hypertension
• Cancer
• Venous thrombosis
• Other cardiovascular diseases

Therefore, detecting cholesterol imbalances early can significantly reduce the risk of these life-threatening diseases.

Point-of-Care Testing: A Major Advantage

In addition to its sensitivity and accuracy, this silk-based sensor has been developed as a point-of-care (POC) diagnostic tool. That means it can be used outside of traditional lab settings, making it ideal for regular health checkups at home, in clinics, or in remote areas.

Tested on Real Samples

The sensor was tested on various real-world samples, including:

• Human blood serum
• Laboratory rat serum
• Milk

In all cases, it responded effectively, confirming its reliability in practical conditions.

Key Researchers and Publication

The project was led by a team that includes:

• Neelotpal Sen Sarma, retired professor
• Dr. Asis Bala, Associate Professor
• Nasrin Sultana, DST INSPIRE Senior Research Fellow

Their findings have been published in the renowned “Nanoscale” journal by the Royal Society of Chemistry.

Conclusion

Thanks to this innovative sensor, monitoring cholesterol levels may soon become easier, more accessible, and eco-friendly. With rising health concerns related to cholesterol, especially in today’s fast-paced lifestyle, such advancements can play a crucial role in promoting preventive healthcare and personalized treatment.

Source: Inputs from various media Sources