

Rural Communities at High Risk of Scrub Typhus Infections
A recent study conducted by researchers at the Christian Medical College (CMC) Vellore has found that people living in rural areas of Tamil Nadu face a high risk of contracting scrub typhus. The study, published in the New England Journal of Medicine, highlights the seriousness of the disease and emphasizes the need for better awareness and diagnostic facilities.
Understanding Scrub Typhus
Scrub typhus is a bacterial infection caused by Orientia tsutsugamushi, which belongs to the rickettsia family. The disease spreads to humans through the bite of infected larval mites, commonly known as chiggers. While many people may not experience symptoms, the infection can sometimes lead to severe illness.
Key Findings of the Study
The research, which involved 32,000 people from rural Tamil Nadu, identified scrub typhus as a major cause of fever-related hospitalizations. Over a two-year period, nearly 10 percent of the population was infected each year. Among them, 8 to 15 percent developed a fever requiring medical treatment, with some needing intensive care.
Dr. Carol Devamani, the study’s lead researcher from CMC Vellore’s Department of Community Medicine, stated, “Following COVID-19, scrub typhus emerged as the most common cause of fever in our study, contributing to nearly 30 percent of fever-related hospital admissions.” However, the disease is frequently overlooked despite the availability of treatment.
Symptoms and Complications
Symptoms of scrub typhus typically appear around 10 days after infection and include:
- Fever
- Headache
- Body aches
- Rash
A black sore, known as an eschar, often forms at the site of the mite bite, making diagnosis easier. If left untreated, scrub typhus can lead to serious complications such as:
- Acute respiratory distress syndrome (ARDS)
- Shock
- Meningitis
- Kidney failure
In severe cases, the infection can be fatal. During the study, five individuals lost their lives due to scrub typhus-related complications.
Treatment and Challenges
Scrub typhus can be effectively treated with antibiotics such as doxycycline and azithromycin. However, there is currently no vaccine available for prevention. The study also pointed out that diagnostic tests are mainly available in larger hospitals, making early detection difficult in rural areas.
Need for Awareness and Better Healthcare Access
The researchers stressed the importance of increasing public awareness about scrub typhus and enhancing local healthcare facilities. Dr. Devamani explained, “Educating communities and strengthening diagnostic capabilities at the local level are crucial steps in reducing unnecessary hospitalizations and preventing fatalities caused by scrub typhus.”
Conclusion
The findings of this study highlight the urgent need for better monitoring, early detection, and improved healthcare services in rural areas. By spreading awareness and making diagnostic tests more accessible, health authorities can help prevent severe cases of scrub typhus and save lives.
Source: Inputs from various media Sources

Priya Bairagi
Reviewed by Dr Aarti Nehra (MBBS, MMST)
I’m a pharmacist with a strong background in health sciences. I hold a BSc from Delhi University and a pharmacy degree from PDM University. I write articles and daily health news while interviewing doctors to bring you the latest insights. In my free time, you’ll find me at the gym or lost in a sci-fi novel.