

This Daily Pill May Prevent Heart Attacks and Strokes
A new oral medication could offer hope for people at high risk of heart attacks and strokes, especially those who haven’t had success with current cholesterol treatments. A recent international study has found that the drug Obicetrapib significantly reduces harmful cholesterol levels and could become an important tool in preventing heart disease.
What Is Obicetrapib?
Obicetrapib is a once-daily pill designed to lower two major contributors to heart disease:
- LDL cholesterol (commonly known as “bad” cholesterol), which can clog arteries
- Lipoprotein(a) or Lp(a), a genetic form of cholesterol that’s harder to treat and increases heart risk
Researchers found that Obicetrapib targets both of these harmful substances effectively.
The Study
The study, published in the New England Journal of Medicine, was led by experts from Monash University in Australia. It included over 2,500 participants with existing heart disease or genetically high cholesterol. These individuals were already taking standard cholesterol medications but needed more help reaching safe levels.
Participants received either Obicetrapib or a placebo along with their usual medication.
Promising Results
After 12 weeks of treatment:
- LDL cholesterol levels dropped by 32.6%
- Lp(a) levels decreased by 33.5%
Many patients achieved cholesterol levels within recommended guidelines for the first time.
Why This Matters
Dr. Stephen Nicholls, the lead researcher and Director of the Victorian Heart Institute, says the findings are significant:
“Many people at high risk of heart attack or stroke don’t get their cholesterol low enough, even on the best available treatments,” he said. “Obicetrapib offers a new option that is both effective and easy to use.”
Unlike other medications, Obicetrapib also reduces Lp(a) — a type of cholesterol that is inherited and difficult to control with current therapies.
Safe and Well-Tolerated
Obicetrapib was found to be safe, with few side effects reported during the trial. It’s a simple once-daily oral dose that adds to its convenience and potential long-term use.
Conclusion
The discovery of Obicetrapib could be a breakthrough for heart patients who are running out of treatment options. With its dual action and strong safety profile, experts believe this pill could play a major role in reducing heart attacks and strokes worldwide.
Source: Inputs from various media Sources

Priya Bairagi
Reviewed by Dr Aarti Nehra (MBBS, MMST)
I’m a pharmacist with a strong background in health sciences. I hold a BSc from Delhi University and a pharmacy degree from PDM University. I write articles and daily health news while interviewing doctors to bring you the latest insights. In my free time, you’ll find me at the gym or lost in a sci-fi novel.