

Schizophrenia, Depression May Double Heart Risk
Summary: Research indicates that both schizophrenia and depression can nearly more than double the likelihood of developing heart disease and experiencing mortality. Understand the major influence mental health has on cardiovascular well-being and recognize the essential importance of integrated care approaches.
Did you know schizophrenia can almost double the risk of heart disease and death?
Schizophrenia and Depression May Double Heart Disease Risk: Lancet Study
A recent study published in The Lancet Regional Health-Europe emphasises a major association between mental health disorders and the development of cardiovascular disease (CVD). Researchers have identified that specific psychiatric conditions notably enhance the risk of heart problems and contribute to higher mortality rates among individuals already diagnosed with cardiovascular issues.
The Connection Between Mental Health Disorders and Heart Disease: An Urgent Concern
Research conducted by Emory University has emphasised important disparities in cardiovascular health among individuals diagnosed with schizophrenia, depression, anxiety, bipolar disorder, and PTSD. The findings emphasise the following associations:
- Schizophrenia: Nearly doubles the risk of cardiovascular disease.
- Major Depression: Corresponds to a 72% increased risk.
- Phobic Anxiety: Associated with a 70% elevation in risk.
- Bipolar Disorder: Contributes to a 61% higher likelihood.
- PTSD: Connected to a 57% increased risk.
- Panic Disorder: Leads to a 50% increased risk.
Enhanced Mortality Rates and Unfavorable Prognosis
The consequences extend beyond mere increased risk, as these mental health conditions are associated withÂ
- Poorer long-term outcomes
- Increased rates of hospital readmissions
- Higher mortality
For example, major depression more than doubles the likelihood of death in patients who already suffer from heart disease.
What Underlies the Strong Connection?
The research emphasises a bidirectional relationship; mental health conditions can contribute to the deterioration of heart health, while cardiovascular issues may, in turn, negatively impact mental well-being.
According to Professor Viola Vaccarino of Emory University, “More than 40% of those with cardiovascular disease also have a mental health condition.”
The Influence of Social Determinants
The research emphasises that social factors play an important role in contributing to adverse cardiovascular outcomes among individuals living with mental health conditions, such as
- Economic accessibility
- Ease of access to healthcare services
- Health literacy
Obstacles to consistent screening and ongoing treatment exacerbate these issues.
Potential Strategies: Towards a Comprehensive Approach
Many experts advocate for integrated, multidisciplinary care that unites behavioural, mental, and cardiovascular healthcare services to address these interconnected health challenges effectively.
Vaccarino suggests: “A clinical team with specialists, social workers, and nurses working together can provide better outcomes.”
Such an approach not only improves health but also upholds the rights of people with mental health conditions to live healthier lives and fully participate in society.
Takeaway
This study emphasizes the critical importance of integrated care models in effectively addressing the complex links between mental health issues and cardiovascular disease. By bridging these health disparities, we have the potential to lower mortality rates and greatly enhance the quality of life for millions of individuals.

Dane
I am an MBBS graduate and a dedicated medical writer with a strong passion for deep research and psychology. I enjoy breaking down complex medical topics into engaging, easy-to-understand content, aiming to educate and inspire readers by exploring the fascinating connection between health, science, and the human mind.